黑料社区

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Andor Kiss
Assistant Professor (Adjunct),
Director - Center for Bioinformatics & Functional Genomics
Microbiology, Biology, Center for Bioinformatics and Functional Genomics

Andor J. Kiss

Contact Info

513-529-4280
86C Pearson Hall

Education

  • PhD; 2005; Ecology, Ethology and Evolution; Department of Animal Biology; University of Illinois at Urbana-Champaign
  • MSc; 1997; Molecular Genetics; Department of Zoology; University of Western Ontario
  • BSc; 1994; Biochemistry and Microbiology; Department of Biochemistry and Microbiology; University of Victoria

Biographical Information

Andor Kiss is the Director of the CBFG, the on-site genomic core facility at 黑料社区. His scientific background is as a biochemist and comparative physiologist with a strong background in molecular biology. His main research interests are in adaptation of vertebrate animals to extreme environments. He has been to Antarctica to study polar fishes. He grew up on Vancouver Island (BC) and is an avid mountain bike rider, former bicycle mechanic, vinyl record collector, and builder of electric guitars.

Research Interests

Biologist. Interested in adaptation and evolution. My objectives are to understand how changes at the molecular level influence the success of the entire organism. Projects include how higher vertebrates have become freeze tolerant, the stability of globular proteins, functional genomics of seasonal acclimations. Applications of this knowledge is (a) understanding of evolutionary biology, (b) tissue and organ preservation, and (c) crewed space flight.

 

Current research projects: (1) Epigenomics of cardiac hypertrophy in murine models, (2) Epigenomics of the wood frog freeze capabilities, (3) Genomic specialisations of the long-lived Greenland shark, and (4) Microbiome adaptations/alterations in guts of humans exposed to GLP1 and how nutrient changes affect metabolic syndrome.

Courses Taught

  • BIO 407/507: Ichthyology (with field component & laboratory)
  • BIO-CHM-MBI (BCM) 424/524: Advanced Experimental Techniques in Structural & Functional Genomics (Laboratory based)

Recent Publications

  • Jiang, Z., Islam, K.N., Wolfe, M., O’Connell, M., Williams, D., Florance, A., Vinyard, D.J., Zhang, X., Brenner, M., Kiss, A.J., et al. (2025). Enhancing photosynthesis under salt stress via directed evolution in cyanobacteria. Pl Physiol, kiaf209. 
  • Krolick, K.N., Cao, J., Gulla, E.M., Bhardwaj, M., Marshall, S.J., Zhou, E.Y., Kiss, A.J., Choueiry, F., Zhu, J., and Shi, H. (2024). Subregion-specific transcriptomic profiling of rat brain reveals sex-distinct gene expression impacted by adolescent stress. Neurosc 553, 19–39. 
  • Smucker, B.J., Wright, S.E., Williams, I., Page, R.C., Kiss, A.J., Silwal, S.B., Weese, M., and Edwards, D.J. (2024). Large Row-Constrained Supersaturated Designs for High-throughput Screening. Preprint at arXiv. 
  • Xu, M., Kiss, A.J., Jones, J.A., McMurray, M.S., and Shi, H. (2024). Effect of oral tryptamines on the gut microbiome of rats—a preliminary study. PeerJ 12, e17517. 
  • Thompson, S.M., Rakoczy, R.J., Duffy, M.A., Kiss, A.J., and McMurray, M.S. (2023). Differential consumption of alcohol, caffeine, and caffeinated alcohol by adolescent rats, and effects on post-adolescent gene expression signatures in the nucleus accumbens and orbitofrontal cortex. Drug and Alcohol Dependence 251, 110921. 
  • Walters, A.D., Arp, A., Cerbie, G.M., Trujillo, D.A., Kiss, A.J., and Berg, D.J. (2022). Phylogenetic relationship and habitat both impact the gut microbiome in two microendemic gastropods. Journal of Molluscan Studies 88, 88. 
  • Rainey, A., Pierce, A., Deng, X., Actis, L.A., Smith, P., Kiss, A.J., and Wilson, T.J. (2021). Validation and deployment of a direct saliva real-time RT-PCR test on pooled samples for COVID-19 surveillance testing. PLOS ONE 16, e0261956. 
  • Oswald KJ, Spinks E, Duktig GS, Baker JS, Kibbey MR, Zimmerman B, Tucker H, Boucher CE, Cincotta DA, Starnes WC, Kiss AJ, Wright JJ, Carlson DM, Bangs MR, Roberts MA, Quattro JM. (2020). Drainage history, evolution, and conservation of tonguetied minnow (Exoglossum laurae), a rare and imperiled teays river endemic. Copeia 108, 381–391. 
  • Posner, M., McDonald, M.S., Murray, K.L., and Kiss, A.J. (2019). Why does the zebrafish cloche mutant develop lens cataract? PLoS One 14, e0211399. 
  • Bierma, J.C., Roskamp, K., Ledray, A., Kiss, A.J., Christina Cheng, C.-H., and Martin, R.W. (2019). Uncovering the Role of Surface Residues and Buffer Composition in Liquid-Liquid Phase Separation of Eye Lens Crystallins from an Antarctic Toothfish. Biophysical Journal 116, 454a. 
  • Bierma, J.C., Roskamp, K.W., Ledray, A.P., Kiss, A.J., Christina Cheng, C.-H., Martin, R.W., Cheng, C.H.C., Martin, R.W., Christina Cheng, C.-H., Martin, R.W., et al. (2018). Controlling Liquid–Liquid Phase Separation of Cold-Adapted Crystallin Proteins from the Antarctic Toothfish. Journal of Molecular Biology 430, 5151–5168. 
  • Teufel, A.G., Li, W., Kiss, A.J., and Morgan-Kiss, R.M. (2017). Impact of nitrogen and phosphorus on phytoplankton production and bacterial community structure in two stratified Antarctic lakes: a bioassay approach. Polar Biology 40, 1007–1022. 
  • Kiss A, Posner M, Mock T. (2015). Seasonally Induced Hepatotranscriptomic Changes in the Freeze Tolerant North American Wood Frog Rana sylvatica. FASEB J 29:981.2.  .
  • Sellin Jeffries, M.K., Kiss, A.J., Smith, A.W., and Oris, J.T. (2014). A comparison of commercially-available automated and manual extraction kits for the isolation of total RNA from small tissue samples. BMC biotechnology 14, 94. 
  • Rosendale, A.J., Costanzo, J.P., Kiss, A.J., and Lee, R.E. (2014). Identification and Expression of a Putative Facilitative Urea Transporter in Three Species of True Frogs (Ranidæ): Implications for Terrestrial Adaptation. Advances in Biology 2014, 1–11. 
  • Posner, M., Kiss, A.J., Skiba, J., Drossman, A., Dolinska, M.B., Hejtmancik, J.F., and Sergeev, Y.V. (2012). Functional Validation of Hydrophobic Adaptation to Physiological Temperature in the Small Heat Shock Protein αA-crystallin. PLOS ONE 7, e34438. 
  • Kiss, A.J., Muir, T.J., Lee, Jr, R.E., and Costanzo, J.P. (2011). Seasonal Variation in the Hepatoproteome of the Dehydration- and Freeze-Tolerant Wood Frog, Rana sylvatica. Int J Mol Sci 12, 8406–8414. 
  • Kiss, A.J., Devries, A.L., and Morgan-Kiss, R.M. (2010). Comparative analysis of crystallins and lipids from the lens of Antarctic toothfish and cow. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 180, 1019–1032. 
  • Mirarefi, A.Y., Boutet, S., Ramakrishnan, S., Kiss, A.J., Cheng, C.-H.C., Devries, A.L., Robinson, I.K., Zukoski, C.F., Mirare, A.Y., Boutet, S., et al. (2010). Small-angle X-ray scattering studies of the intact eye lens: effect of crystallin composition and concentration on microstructure. Biochimica et biophysica acta 1800, 556–564. 
  • Kiss, A.J., and Cheng, C.-H.C. (2008). Molecular diversity and genomic organisation of the α, β and γ eye lens crystallins from the Antarctic toothfish Dissostichus mawsoni. Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics 3(2), 155–171. 
  • Kiss, A.J. (2008). The Antarctic Toothfish: A New Model System for Eye Lens Biology. In Animal Models in Eye Research, P. A. Tsonis, ed. (Academic Press), pp. 48–56. 
  • Kiss, A.J. (2005). Functional, Biochemical and Molecular Analyses of the Cold Stable Eye Lens Crystallins from the Antarctic toothfish Dissostichus mawsoni. PhD Dissertation. UIUC. pp 184. [Free PDF]
  • Kiss, A.J., Mirarefi, A.Y., Ramakrishnan, S., Zukoski, C.F., Devries, A.L., and Cheng, C.H. (2004). Cold-stable eye lens crystallins of the Antarctic nototheniid toothfish Dissostichus mawsoni Norman. J Exp Biol 207, 4633–4649. 
  • Kiss, A.J., Farah, K., Kim, J., Garriock, R.J., Drysdale, T. a, and Hammond, J.R. (2000). Molecular cloning and functional characterization of inhibitor-sensitive (mENT1) and inhibitor-resistant (mENT2) equilibrative nucleoside transporters from mouse brain. The Biochemical journal 352, 363–372. 
  • Kiss, A.J. (1997). A spatial and temporal study of mRNA binding proteins specific to a 134 base CA dinucleotide-rich portion of the 3’-untranslated region from the BALB/c mouse catalase gene, Cas-1. MSc. Thesis. University of Western Ontario. pp 113. [Free PDF].
  • Hunt, J.G., Kasinsky, H.E., Elsey, R.M., Wright, C.L., Rice, P., Bell, J.E., Sharp, D.J., Kiss, A.J., Hunt, D.F., Arnott, D.P., et al. (1996). Protamines of reptiles. J Biol Chem 271, 23547–23557. 

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