Jon Stavres
Educational Credentials
- Postdoc, Cardiovascular Physiology, Penn State Heart and Vascular Institute
- Ph.D., Exercise Physiology, Kent State University
- M.S., Exercise Science, Indiana University of Pennsylvania
- B.S. Exercise Science, Indiana University of Pennsylvania
Biography
Jon Stavres earned his Ph.D. in Exercise Physiology from Kent State University under the mentorship of Dr. John McDaniel, after which he completed his postdoctoral training at the Penn State Heart and Vascular Institute with Dr. Lawrence I. Sinoway.
Professional Affiliations
- American Physiological Society- Professional Member
- American College of Sports Medicine- Professional Member
Research Interests
My research interests are centered around the control of blood pressure and blood flow at rest and during exercise in humans. It is widely understood that blood pressure increases in response to exercise, which is necessary for increasing blood flow, and thus convective oxygen transport, to the active skeletal muscle. However, the physiological mechanisms governing these responses are both complex and fascinating. Much of my work focuses on the afferent exercise pressor reflex, which is comprised of the muscle mechano- and metaboreflex pathways. Through our work in healthy adults, we have shown that the exercise pressor reflex exerts an additive influence when combined with other sympathetic stimuli, such as the Valsalva maneuver, and we have also shown that the magnitude of the exercise pressor response is largely tied to strength and fat-free mass. Furthermore, we also found evidence that individuals with cardiometabolic disorders (e.g., metabolic syndrome) demonstrate significantly exaggerated exercise pressor and metaboreflex responses, which is not solely explained by the individual components of metabolic syndrome (e.g., hypertension, central obesity, or hyperglycemia). In recent years, our team has continued to pursue questions related to autonomic and cardiovascular function in individuals with cardiometabolic disorders, and this line of investigation has been supported by over $300,000 in NIH funding. Here at Miami, we are continuing this line of study, while also exploring novel treatment options for mitigating exaggerated blood pressure responses and examining the effects of GLP-1 use in individuals with cardiometabolic disease.
As a 黑料社区 in my lab, you will play a very important role in these projects, Prior to joining Miami, I served as a faculty member at the University of Southern Mississippi for four years. There, I mentored ten undergraduate 黑料社区s and eight graduate 黑料社区s, all of whom were trained to collect, analyze, and disseminate research data. Through their work in the lab, these 黑料社区s have earned authorship on twenty peer-reviewed scientific manuscripts, four of which are first-authored by 黑料社区s. Likewise, two of these undergraduate 黑料社区s were named Scholar Athlete of the Year, two of these graduate 黑料社区s were named to the USM Graduate School Hall of Fame, and one is currently the vice president of his medical school class. Ultimately, each of these 黑料社区s have been able to leverage their experiences in the lab to advance their careers after graduation. If you are interested in joining the lab, or just want to ask some questions, please feel free to fill out the Google form in the “links” section.
Courses Taught
- KNH 382 Physical Activity and Fitness Assessment (2 sections)
Recent Grants
- Implications of Exaggerated Metaboreflex Responses in Metabolic Syndrome
- Mississippi Center for Clinical and Translational Research Pilot Project Program
- NIGMS | 5U54GM115428-09 (SP5111-SB36)
- Amount Funded- $59,200 (2024)
- Role- PI
- A Multi-Modal Approach to Improving Early Detection of Cardiometabolic Risk in Young Adults in Mississippi
- Mississippi Center for Clinical and Translational Research Administrative Supplement Award
- NIH | NIGMS | U54GM115428-08
- Amount funded- $1,127,454 (2023-2024)
- Project 2 amount- $269,260
- Role- Project 2 Lead Investigator (PI: J. Granger)
- The Effect of a Hip Flexion Feedback System for Exercise in Individuals with Osteoarthritis and Obesity
- American Heart Association Institutional Research Enhancement Award
- Amount funded- $151,615 (2023-2025)
- Role- Co-Investigator (PI: N. Oliveira)
- Sympathetic Control of Blood Pressure in Black and African American Individuals with Metabolic Dysfunction, and Influence of Acute Ketone Ester Administration
- NIH Division of Loan Repayment | NHLBI | 2L60HL154357-02
- Loan Repayment Program (LRP) (2023)
- Role- PI / Awardee
- Effects of Acute Exercise on Sympathetically Mediated Blood Pressure Regulation
- University of Southern Mississippi
- Aubrey Keith and Ella Gin Lucas Endowment for Faculty Excellence Award
- Amount funded- $5,000 (2021-2023)
- Role-PI
- Cerebrovascular Responses to Acute Ketone Ester Administration: A Pilot Study
- University of Southern Mississippi- College of Education and Human Sciences
- Interdisciplinary Project Grant
- Amount funded- $5,000 (2022-2023)
- Role- PI (Co-PI A.J. Graybeal)
- Sympathetic Control of Skeletal Muscle Oxygen Transport in Peripheral Arterial Disease
- NIH Division of Loan Repayment | NHLBI | 2L60HL154357
- Loan Repayment Program (LRP) (2020)
- Role- PI / Awardee
- A Double-Blind Randomized Placebo-Controlled Study on the Analgesic Properties of Amiloride in
- Exercise-Induced Skeletal Muscle Pain
- Penn State Hershey Department of Anesthesiology & Perioperative Medicine
- Resource Allocation Panel (RAP) Research Grant
- Amount funded- $8,160 (2020)
- Role- Co-Investigator (PI: V. Ruiz-Velasco)
Select Publications
(*corresponding author, †黑料社区/trainee primary author)
- *Stavres J, Aultman RS, Brandner CF, Vallecillo-Bustos A, Compton AT, Swafford SH, Newsome TA, Graybeal AJ. (2025). Influence of exogenous ketosis on spontaneous cardiovagal baroreflex gain and blood pressure responses to isometric handgrip in individuals with metabolic syndrome: A placebo-controlled pilot study. European Journal of Applied Physiology, [Online Ahead of Print]. DOI: 10.1007/s00421-025-05921-z
- Graybeal AJ, Compton AT, Swafford SH, Brandner CF, Johnson MF, Kaylor MG, Haynes H, Stavres J. (2025). A predictive model for body water and fluid balance using 3D smartphone anthropometry. Frontiers in Physiology, 16. DOI: 10.3389/fphys.2025.1577049
- Graybeal AJ, Aultman RS, Brandner CF, Vallecillo-Bustos A, Compton AT, Swafford SH, Newsome TA, Stavres J. (2025). The effects of an oral ketone ester on appetite, food intake, and cognition in individuals with metabolic syndrome: A randomized, single-blind, placebo-controlled, matched pairs crossover trial. Journal of Dietary Supplements, 22(3), 382-400. DOI: 10.1080/19390211.2025.2473371.
- *Stavres J, Vallecillo-Bustos A, Parnell S, Aultman RS, Newsome TA, Swafford SH, Compton AT, Schimpf RC, Schmidt SN, Lee C, Graybeal AJ. (2025). Peripheral vasoconstriction is not elevated during hyperreactive responses to the cold pressor test: A cross-sectional study. Frontiers in Physiology, 16, DOI: 10.3389/fphys.2025.1532992.
- †Newsome TA, Graybeal AJ, Aultman RS, Vallecillo-Bustos A, Brandner CF, Swafford SH, Compton AT, Parnell S, Schimpf R, Thorsen TA, Renna ME, *Stavres J. (2025). Examining the use of a continuous marker of metabolic syndrome severity for detecting resting autonomic dysfunction in a multiracial sample of young adults. Frontiers in Cardiovascular Medicine, 12, 1-9. DOI: 10.3389/fcvm.2025.1508805.
- Renna ME, Willbourne FN, Johal S, Fergerson AK, Behringer KF, Brandner CF, Stavres J, Graybeal AJ. (2025). Stress and anxiety are associated with increased metabolic syndrome risk among young adults living in the deep south. Healthcare, 12(4). DOI: 10.3390/healthcare13040359
- Graybeal AJ, Swafford SH, Compton AT, Renna ME, Thorsen T, Stavres J. (2024). Predicting bone mineral content from smartphone digital anthropometrics: Evaluation of an existing application and the development of new prediction models. Journal of Clinical Densitometry, 28(1). DOI: https://doi.org/10.1016/j.jocd.2024.101537.
- Graybeal AJ, Brandner CF, Compton AT, Swafford SH, Aultman RS, Vallecillo-Bustos A, Stavres J. (2024). Differences in metabolic syndrome severity and prevalence across nine waist circumference measurements collected from smartphone digital anthropometrics. Clinical Nutrition ESPEN, 64, 390-399. DOI: 10.1016/j.clnesp.2024.10.158
- Brandner CF, Compton AT, Swafford SH, Aultman RS, Vallecillo-Bustos A, Newsome TA, Renna ME, Thorsen T, Stavres J, Graybeal AJ. Total and appendicular body composition comparisons between near-infrared reactance spectroscopy and dual energy x-ray absorptiometry. Clinical Physiology and Functional Imaging, 1-13. DOI: 10.1111/cpf.12914
- Graybeal AJ, Stavres J, Swafford SH, Compton AT, McCoy S, Huye H, Thorsen T, Renna ME. (2024). The associations between depression and added and relative sugar consumption are mediated by emotional eating and craving control in multi-ethnic young adults. Healthcare, 12(19), 1-16. DOI: 10.3390/healthcare12191944.
- †Parnell S, Graybeal AJ, Renna ME, *Stavres J. (2024). Preliminary evaluation of self-reported training volume as an adjunct measure of female athlete triad risk in division 1 collegiate female runners. Journal of Functional Morphology and Kinesiology, 9(4), 1-14. DOI: 10.339/jfmk9040179.
- Fernandes IA, Stavres J, Hamaoka T, Ojikutu Q, Sabino-Carvalho J, Vianna L, Luck JC, Blaha C, Cauffman A, Dalton P, Herr MD, Ruiz-Velasco V, Carr Z, Janicki P, Cui J. (2024). Does a single oral administration of amiloride affect spontaneous baroreflex sensitivity and blood pressure variability in healthy young adults? The Journal of Neurophysiology, 13(3), 922-928. DOI: 10.1152/jn.00264.2024.
- Graybeal AJ, Brandner CF, Wise HL, Henderson A, Aultman RS, Vallecillo-Bustos A, Newsome TA, Stanfield D, Stavres J. (2024). Near-infrared reactance spectroscopy-derived visceral adipose tissue for the assessment of metabolic syndrome in a multi-ethnic sample of young adults. Journal of Human Biology, 1-16. DOI: 10.1002ajhb.24141
- *Stavres J, Vallecillo-Bustos A, Newsome TA, Aultman R, Brandner C, Graybeal AJ. (2024). Hemodynamic responses to the cold pressor test in individuals with metabolic syndrome: A case-control study in a multiracial sample of adults. Journal of Human Hypertension, 38(9), 655-662. DOI: 10.1038/s41371-024-00938-x.
- †Vallecillo-Bustos A, Compton AT, Swafford SH, Renna M, Thorsen T, Stavres J, Graybeal AJ. (2024). The effect of postural orientation on body composition and total body water estimates produced by smartwatch bioelectrical impedance analysis: An intra- and inter-device evaluation. Journal of Bioelectrical Impedance, 15(1), 89-98. DOI: https://doi.org/10.2478/joeb-2024-0010.
- Graybeal AJ, Compton AT, Swafford SH, Brandner CF, Thorsen T, Renna M, Stavres J. (2024). Measurements of abdominal obesity are associated with metabolic syndrome severity independent of hypertensive phenotype in White but not Black adults. Journal of Racial and Ethnic Health Disparities, [Accepted June 1st, 2024]. DOI: 10.1007/s40615-024-02051-8.
- *Stavres J, Aultman RS, Brandner CF, Newsome TA, Vallecillo-Bustos A, Graybeal AJ. (2024). Fat-free mass is associated with exercise pressor responses, but not cold-pressor responses, in humans: Influence of Maximal Voluntary Contraction. Frontiers in Sports and Active Living, 6. DOI: 10.3389/fspor.2024.1352192.
- Thorsen T, Oliveira N, Graybeal, AJ, Stavres J. Exploring gait velocity as a predictor of cardiometabolic disease risk in young adults. (2024). Frontiers in Sports and Active Living, 6. DOI: 10.3389/fspor.2024.1365717.
- Mannozzi J, Massoud L, Stavres J, Al-Hassan MH, O’Leary D. (2023). Autonomic function and metabolic syndrome components: Are the symptoms additive or multiplicative. Journal of Clinical Medicine, 3(13). DOI: 10.3390/jcm13030895.
- *Stavres J, Aultman RS, Newsome TA. (2023). Exercise pressor responses are exaggerated relative to force production during, but not following, thirty-minutes of rhythmic handgrip exercise. European Journal of Applied Physiology, 124(5). DOI: 10.1007/s00421-023-05390-2.
- Graybeal AJ, Brandner CF, Compton AT, Swafford SH, Henderson A, Aultman RS, Vallecillo-Bustos A, Stavres J. (2023). Smartphone derived anthropometrics: Agreement between a commercially available smartphone application and its parent application intended for use at point-of-care. Clinical Nutrition ESPEN, 59,107-113. DOI: 10.1016/j.clnesp.2023.11.021.
- Graybeal AJ, Brandner CF, Wise HL, Henderson A, Aultman RS, Vallecillo-Bustos A, Newsome TA, Stanfield D, & Stavres J. (2023). Associations between eating behaviors and metabolic syndrome severity in young adults. Eating Behaviors, 51, 2-6. DOI: 10.1016/j.eatbeh.2023.101821.
- Graybeal AJ, Brandner CF, Stavres J. (2023). Paradoxical associations among bioelectrical impedance and cardiometabolic health parameters in young White and Black adults. Medicine & Science in Sport & Exercise, 56(3), 418-426. DOI: 10.1249/MSS.0000000000003321.
- *Stavres J, Aultman RA, Brandner CF, Newsome TA, Vallecillo-Bustos A, Wise HL, Henderson A, Stanfield D, Mannozzi J, Graybeal AJ. (2023). Hemodynamic responses to handgrip and metaboreflex activation are exaggerated in individuals with metabolic syndrome independent of resting blood pressure, waist circumference, and fasting blood glucose. Frontiers in Physiology, 7(14). DOI: 10.3389/fphys.2023.1212775.
- *Stavres J, Faulkner B, Haynes H, Newsome T, Dearmon M, Ladner KR, Luck JC. (2023). Additive influence of exercise pressor reflex activation on Valsalva responses in White and Black adults. European Journal of Applied Physiology, 123(10), 2259-2270. DOI: 10.1007/s00421-023-05240-1.
- Oliveira N, Keating CJ, Chiu CY, Stavres J. (2023). Increased hip flexion as an exercise modality for individuals with obesity. European Journal of Applied Physiology, 123(10), 2157-2165. DOI: 10.1007/s00421-023-05227-y.
- †Luck JC, Sica CT, Blaha C, Cauffman A, Vesek J, Eckenrode J, & *Stavres J. (2023). Agreement between multiparametric MRI (PIVOT), Doppler ultrasound, and near-infrared-spectroscopy based assessments of skeletal muscle oxygenation and perfusion. Magnetic Resonance Imaging, 96, 27-37. DOI: 10.1016/j.mri.2022.11.003. PMCID: PMC9789193.
- Graybeal AJ, Brandner CF, Tinsley GM, Haynes H, Stavres J. (2022). Associations between visceral adipose tissue estimates produced by near-infrared spectroscopy, mobile anthropometrics, and traditional body composition assessments and estimates derived from dual-energy x-ray absorptiometry. British Journal of Nutrition, 1-11. DOI: 10.1017/S0007114522003488.
- †Wright A, Stavres J, Galloway R, Donahue P, Sha Z, McCoy S. (2022). Aortic stiffness increases during prolonged sitting independent of intermittent standing or prior exercise. European Journal of Applied Physiology, 123(3). DOI: 10.1007/s00421-022-05079-y.
- *Stavres J, Luck JC, Hamaoka T, Blaha C, Cauffman AE, Dalton PC, Herr MD, Ruiz-Velasco V, Carr Z, Janicki P, & Cui J. (2022). A 10mg dose of amiloride increases time to failure during blood-flow-restricted plantar flexion in healthy adults without influencing blood pressure. American Journal of Physiology- Regulatory, Integrative and Comparative Physiology, 323(6). DOI: 10.1152/ajpregu.00190.2022.
Ad-Hoc Reviewer
- Journal of Physiology
- Hypertension
- Journal of Human Hypertension
- Experimental Physiology
- Frontiers in Medicine
- Frontiers in Nutrition
- Research Directs in Health Sciences
- Preventative Medicine Reports
- Scientific Reports
- European Journal of Applied Physiology
- BMC Musculoskeletal Disorders
- Journal of Clinical Medicine
- Physiological Reports
- Journal of Functional Morphology and Kinesiology
- Life
- Applied Sciences
- Research Quarterly for Exercise and Sport
- Journal of Spinal Cord Medicine
- Scandinavian Journal of Medicine and Science in Sports
- International Journal of Exercise Science
In the News
- USM News / Talon Magazine article- NIH Awards $800K to USM Faculty Studying Cardiometabolic Diseases. Nov 2023.
- MCCTR Newsletter Vol 3 Issue 1- MCCTR Investigator Spotlight: Pilot Projects Program Investigators. Feb 2025.